Improper lengths of actin-thin filaments are associated with altered contractile activity and lethal myopathies.Leiomodin, a member of the tropomodulin family of proteins, is critical in thin filament assembly and maintenance; however, its role is under dispute.Using nuclear magnetic resonance data and molecular dynamics simulations, we generated t
Macrophages are dynamic cells that play critical roles in the induction and resolution of sterile inflammation.In this review, we will compile and interpret recent findings on the plasticity of macrophages and how these cells contribute to the development of rail cover non-infectious inflammatory diseases, with a particular focus on allergic and au
Abstract Background Item response theory (IRT) is extensively used to develop adaptive instruments of health-related quality of life (HRQoL).However, each IRT model has its own function to estimate item and category parameters, and hence different results may be found using Backpacks the same response categories with different IRT models.The presen